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Drug ReportsDiatrizoate meglumine
Diatrizoate meglumine
Cystografin, Diatrizoate Diatrizoate, Gastrografin, Hypaque, Md, Md-gastroview, Sinografin, Urovist (diatrizoate meglumine) is a small molecule pharmaceutical. Diatrizoate meglumine was first approved as Cystografin on 1982-01-01.
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Commercial
Clinical
Drug
Target
Variants
Financial
Trends
Safety
Events Timeline
5D
1M
3M
6M
YTD
1Y
2Y
5Y
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FDA approval date
EMA approval date
Patent expiration date
Study first post date
Last update post date
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Completion date
Results first post date
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Commercial
Therapeutic Areas
No data
Trade Name
FDA
EMA
Cystografin (discontinued: Angiovist, Cardiografin, Hypaque, Md, Reno, Urovist, Urovist cysto)
Combinations
Gastrografin (generic drugs available since 1982-01-01, discontinued: Angiovist, Gastrovist, Hypaque, Md, Md-76r, Renocal, Renografin, Renovist, Sinografin)
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Diatrizoate meglumine
Tradename
Company
Number
Date
Products
CYSTOGRAFIN DILUTEBracco DiagnosticsN-010040 RX1982-11-09
1 products, RLD
CYSTOGRAFINBracco DiagnosticsN-010040 RX1982-01-01
1 products, RLD
Show 7 discontinued
Diatrizoate meglumine
+
Diatrizoate sodium
Tradename
Company
Number
Date
Products
GASTROGRAFINBracco DiagnosticsN-011245 RX1982-01-01
1 products, RLD, RS
Show 7 discontinued
Diatrizoate meglumine
+
Iodipamide meglumine
Tradename
Company
Number
Date
Products
SINOGRAFINBracco DiagnosticsN-011324 DISCN1982-01-01
1 products, RLD
Hide discontinued
Diatrizoate sodium
Tradename
Company
Number
Date
Products
HYPAQUEGE HealthcareN-009561 DISCN1982-01-01
1 products
HYPAQUE SODIUM 20%GE HealthcareN-009561 DISCN1982-01-01
1 products
HYPAQUEGE HealthcareN-009561 DISCN1982-01-01
1 products
HYPAQUEGE HealthcareN-011386 DISCN1982-01-01
2 products
Hide discontinued
Labels
FDA
EMA
Brand Name
Status
Last Update
cystografinNew Drug Application2018-04-15
cystografin diluteNew Drug Application2018-10-02
diatrizoate meglumine and diatrizoate sodiumANDA2024-04-23
gastrografinNew Drug Application2021-10-04
hypaque2006-04-13
hypaque - cysto2007-08-03
hypaque sodium2007-08-03
md gastroviewANDA2021-01-01
md-gastroviewANDA2014-09-29
Indications
FDA
EMA
No data
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
V: Various drug classes in atc
— V08: Contrast media
— V08A: X-ray contrast media, iodinated
— V08AA: Watersoluble, nephrotropic, high osmolar x-ray contrast media
— V08AA01: Diatrizoic acid
HCPCS
No data
Clinical
Clinical Trials
43 clinical trials
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Indications Phases 4
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Intestinal obstructionD007415—K56.60—123510
GallstonesD042882EFO_0004210————112
CholelithiasisD002769EFO_0004799K80———112
CholecystolithiasisD041761EFO_1000864————112
IleusD045823———111—2
Hepatocellular carcinomaD006528—C22.0———1—1
Liver neoplasmsD008113EFO_1001513C22.0———1—1
Healthy volunteers/patients——————1—1
Congenital abnormalitiesD000013EFO_0003915Q89.9———1—1
GastroschisisD020139EFO_1000949Q79.3———1—1
Show 4 more
Indications Phases 3
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Type 2 diabetes mellitusD003924EFO_0001360E11—22——2
CardiomyopathiesD009202EFO_0000318I42121——2
Dilated cardiomyopathyD002311HP_0001644I42.0121——2
Colonic neoplasmsD003110—C18——1—12
Insulin resistanceD007333HP_0000855——11——1
Diabetes mellitusD003920HP_0000819E08-E13—11——1
InfertilityD007246HP_0000789———1——1
FlushingD005483—R23.2——1——1
Pathologic constrictionD003251————1——1
Urethral strictureD014525HP_0012227———1——1
Show 3 more
Indications Phases 2
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
ConstipationD003248HP_0002019K59.0—1———1
Fecal impactionD005244—K56.41—1———1
Liver cirrhosisD008103EFO_0001422K74.011———1
FibrosisD005355——11———1
Indications Phases 1
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Behcet syndromeD001528EFO_0003780M35.21————1
RetinitisD012173—H30.91————1
Knee osteoarthritisD020370EFO_0004616M171————1
OsteoarthritisD010003EFO_0002506M15-M191————1
AdenocarcinomaD000230——1————1
Adenocarcinoma of lungD000077192——1————1
Cellular immunityD007111——1————1
Indications Without Phase
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Esophageal achalasiaD004931HP_0002571K22.0————22
Colorectal neoplasmsD015179——————22
Underactive urinary bladderD000077295——————22
HypokinesiaD018476——————22
Urinary bladder neck obstructionD001748EFO_1000840N32.0————22
CystoceleD052858——————22
Esophageal motility disordersD015154—K22.4————11
Muscle spasticityD009128HP_0001257—————11
Diffuse esophageal spasmD015155EFO_1001785K22.4————11
Esophageal diseasesD004935EFO_0009544K22.9————11
Show 15 more
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameDiatrizoate meglumine
INNsodium amidotrizoate
Description
Amidotrizoic acid is a member of the class of benzoic acids that is benzoic acid having iodo substituents at the 2-, 4- and 6-positions and acetamido substituents at the 3- and 5-positions. It is used, mainly as its N-methylglucamine and sodium salts, as an X-ray contrast medium in gastrointestinal studies, angiography, and urography. It has a role as a radioopaque medium, an environmental contaminant and a xenobiotic. It is an organoiodine compound, a member of benzoic acids and a member of acetamides. It is a conjugate acid of an amidotrizoic acid anion.
Classification
Small molecule
Drug class—
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Structure (InChI/SMILES or Protein Sequence)
CC(=O)Nc1c(I)c(NC(C)=O)c(I)c(C(=O)O)c1I.CNC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO
Identifiers
PDB—
CAS-ID131-49-7
RxCUI—
ChEMBL IDCHEMBL1200839
ChEBI ID31812
PubChem CID2140
DrugBankDB00271
UNII IDV5403H8VG7 (ChemIDplus, GSRS)
Target
No data
Variants
No data
Financial
No data
Trends
PubMed Central
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Additional graphs summarizing 31,144 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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347 adverse events reported
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